Results

Results from 2005 - 2010:

IVF/ICSI (TESA included)		2005 -2009	2010
Women less than 35 years	positive pregnancy test after embryo transfer	44,3%	59,7%
Women less than 35 years	living foetus week 8	37,7%	53,6%

Women 35 - 39 years	positive pregnancy test after embryo transfer	38,1%	43,4%
Women 35 - 39 years	living foetus week 8	29,8%	33,3%

Women 40 - 43 years	positive pregnancy test after embryo transfer	28,0%	27,5%
Women 40 - 43 years	living foetus week 8	19,10%	18,7%

Our results for 2010 once more surpass the Danish National IVF results, where 30.7 % of women < 40 years had a living foetus/embryo transfer and 13,5 % of women over 40 years (www.fertilitetsselskab.dk, årsrapporter).

Our success in the younger aged women is especially due to the fact, that we have performed more blastocyst transfers in women with several good quality embryos on day 2 instead of transferring 4-cell embryos. With the introduction of vitrification this spring, over 90 % of vitrified blastocysts survive the thawing process. Our results include all women that had an embryo transfer, also those with day-2 transfer. If we only look at women with blastocyst transfer, 65% became pregnant.

There are many reasons why in vitro fertilisation does not result in pregnancy – and new reasons are discovered all the time.

The following factors may play a part:

The woman’s age determines the pregnancy rate
Even embryos that look normal may stop developing
The uterine mucosa is unable to receive the embryos at the time of transfer
Uterine fibromas reduce the pregnancy potential
Hydrosalpinges (fallopian tubes filled with fluid) reduce the pregnancy potential
Endometriosis interferes with oocyte and endometrial quality
Very reduced sperm quality decreases the chance of correct fertilization

Insemination with the husbands semen		2005 -2008	2009
Women less than 35 years	positive pregnancy test	18,2%	19,5%
Women less than 35 years	living foetus week 8	15,9%	16,8%

Women 35 - 39 years	positive pregnancy test	17,5%	16,0%
Women 35 - 39 years	living foetus week 8	14,5%	13,6%

Women 40 - 43 years	positive pregnancy test	13,6%	12,0%
Women 40 - 43 years	living foetus week 8	8,5%	10,7%

For comparison, the Danish National data report 14,7% living foetus per insemination for all women less than 40 years and 5,6% for women 40 years and older. The pregnancy rates for women over 43 years are extremely low. Therefore, we do not perform inseminations in this group but recommend IVF.

Insemination with donor semen		2005 -2008	2009
Women less than 35 years	positive pregnancy test	22,0%	33,1%
Women less than 35 years	living foetus week 8	19,2%	27,1%

Women 35 - 39 years	positive pregnancy test	20,8%	23,3%
Women 35 - 39 years	living foetus week 8	15,7%	19,0%

Women 40 - 43 years	positive pregnancy test	12,0%	12,0%
Women 40 - 43 years	living foetus week 8	8,3%	7,2%

For comparison, the Danish National data report 13,6% living foetus per insemination for all women less than 40 years and 4,9% for women 40 years and older. The pregnancy rates for women over 43 years are extremely low. Therefore, we do not perform inseminations in this group but recommend IVF.